The project

Severe Neonatal Infection Adaptive Platform Trials in Africa (SNIP-AFRICA) is a 5-year project (2023-2028) that aims to reduce mortality among neonates in hospital with sepsis in Africa.

To better treat neonatal sepsis in the face of rising antimicrobial resistance, SNIP-AFRICA seeks to develop a clinical research platform for the implementation of adaptive trials in sub-Saharan Africa. 

SNIP-AFRICA will conduct a trial, which will enrol 1,200 neonates across neonatal units in Ghana, Kenya, South Africa, Tanzania and Uganda. The trial will identify optimal treatment regimens and doses for difficult-to-treat infections and sepsis.


SNIP-AFRICA sets out to:



SNIP-AFRICA expects to attain: